Skole, an unranked prospect seen as a potential difference-maker, tested positive for a performance-enhancing amphetamine. After his appeal was denied, the ban was made effective immediately.
"It is what it is," Texas general manager Jon Daniels told MLB.com. "He made a mistake. That's what the system is for. He'll serve his punishment."
The 20-year-old outfielder was batting .185 with 11 extra-base hits and 18 RBIs in 68 games for the Class A Advanced Myrtle Beach Pelicans. He last played Thursday and was mired in a 1-for-37 slump at the plate that spanned a dozen games.
"It's probably affected his play overall the last few weeks," Daniels said. "He's struggled while it's been on his mind. That's the challenge for Jake -- to make the best use of his time on and off the field, physically and mentally. The talent is there. He's had a rough year between the lines, and this. This is an opportunity for him to get things right."
A native of Woodstock, Ga., Skole was named the Carolina League Player of the Week last May 29.
Skole also showed promise in his second pro season in 2011, posting .264/.366/.755 marks and stealing 21 bases in 124 games at Class A Hickory.
Skole became the 51st Minor League ballplayer this year to be suspended under the program.